Allosteric Modulation
Allosteric modulation provides new dimensions of drug activity and avenues for target selectivity. Numerous investigators have derived equations for analyzing allosteric pharmacology data. We installed these equations in a free plugin for GraphPad Prism so you can use them easily.
Allosteric modulation provides new dimensions of drug activity and avenues for target selectivity. Numerous investigators have derived equations for analyzing allosteric pharmacology data.
We installed these equations as a free plugin for GraphPad Prism. For information check out the PDF below. Prism files and other documentation can be found here.
Pharmechanics has > 25 years experience in allosteric pharmacology. We can support your data analysis and interpretation in allosteric modulator drug discovery programs. See our papers here.
Related
Resources
Allosteric Modulator Analysis
How to perform allosteric modulator analysis in GraphPad Prism
Allosteric equations
Allosteric binding and signaling equations in GraphPad Prism template files
Why Choose Pharmechanics?
Pharmechanics was founded by Dr Sam Hoare in 2017, with the goal of helping pharmacologists analyze, interpret and apply their data to accelerate drug discovery and basic research on drug targets. See testimonials here to see how I can support your science.
Sam is a globally-recognized expert on industrial, applied and theoretical pharmacology. As Lead Pharmacologist at Neurocrine Biosciences, his leadership, experience and insights were instrumental in the pharmacological optimization of three novel FDA-approved therapeutics, and several more compounds in clinical development.