Kinase Residence Time
At Pharmechanics we have often been asked about analyzing kinase inhibitor residence time experiments, in which inhibitor is applied, free inhibitor washed out, and dissociation of inhibitor measured by it’s ability to impede association of a tracer.
We developed a simple custom equation and loaded it into GraphPad Prism ready for you to use.
Check out the PDF below and obtain the GraphPad Prism template from here.
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Why Choose Pharmechanics?
Pharmechanics was founded by Dr Sam Hoare in 2017, with the goal of helping pharmacologists analyze, interpret and apply their data to accelerate drug discovery and basic research on drug targets. See testimonials here to see how I can support your science.
Sam is a globally-recognized expert on industrial, applied and theoretical pharmacology. As Lead Pharmacologist at Neurocrine Biosciences, his leadership, experience and insights were instrumental in the pharmacological optimization of three novel FDA-approved therapeutics, and several more compounds in clinical development.